Florian Bonn Selected Research

m-AAA proteases

10/2011	Whole-exome sequencing identifies homozygous AFG3L2 mutations in a spastic ataxia-neuropathy syndrome linked to mitochondrial m-AAA proteases.
5/2010	Functional evaluation of paraplegin mutations by a yeast complementation assay.
10/2009	Autocatalytic processing of m-AAA protease subunits in mitochondria.

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Florian Bonn Research Topics

Disease

3	Neoplasms (Cancer) 01/2022 - 01/2018
2	Bacterial Infections (Bacterial Infection) 10/2021 - 01/2018
2	Infections 10/2021 - 01/2018
2	Type 2 Diabetes Mellitus (MODY) 01/2016 - 07/2015
2	Hereditary Spastic Paraplegia 10/2011 - 05/2010
2	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2010 - 10/2009
1	Neoplasm Metastasis (Metastasis) 03/2022
1	Prostatic Neoplasms (Prostate Cancer) 03/2022
1	Biotin deficiency 02/2022
1	Colitis 02/2022
1	Inflammation (Inflammations) 02/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 02/2022
1	Paralysis (Palsy) 11/2021
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020
1	Genomic Instability 01/2020
1	Glioma (Gliomas) 03/2019
1	Liver Failure 08/2018
1	Fibrosis (Cirrhosis) 08/2018
1	Brain Diseases (Brain Disorder) 08/2018
1	Triple Negative Breast Neoplasms 01/2018
1	Breast Neoplasms (Breast Cancer) 01/2018
1	Staphylococcal Infections 12/2013
1	Spastic Ataxia 10/2011
1	Spinocerebellar Degenerations (Marinesco Sjogren Syndrome) 04/2010
1	Paraplegia (Spastic Paraplegia) 04/2010

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 02/2022 - 10/2011
3	m-AAA proteasesIBA 10/2011 - 10/2009
2	Peptide Hydrolases (Proteases)FDA Link 01/2020 - 04/2010
2	Pharmaceutical PreparationsIBA 01/2016 - 07/2015
2	Acarbose FDA LinkGeneric 01/2016 - 07/2015
1	Cholecalciferol (Vitamin D3)FDA Link 03/2022
1	Zoledronic Acid (Zometa)FDA Link 03/2022
1	Vitamin D FDA LinkGeneric 03/2022
1	Calcitriol (Calcijex)FDA LinkGeneric 03/2022
1	hydroxide ionIBA 03/2022
1	Carnitine (L-Carnitine)FDA LinkGeneric 02/2022
1	Biotin (Vitamin H)FDA Link 02/2022
1	C-Reactive ProteinIBA 02/2022
1	SodiumIBA 02/2022
1	Transcription Factors (Transcription Factor)IBA 02/2022
1	Dextran SulfateIBA 02/2022
1	Peptides (Polypeptides)IBA 11/2021
1	Amyloid (Amyloid Fibrils)IBA 11/2021
1	Serine (L-Serine)FDA Link 10/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2020
1	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2020
1	Arsenic Trioxide (Trisenox)FDA Link 03/2019
1	GossypolIBA 03/2019
1	GANT 61IBA 03/2019
1	Antineoplastic Agents (Antineoplastics)IBA 03/2019
1	AlbuminsIBA 08/2018
1	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2018
1	UbiquitinIBA 01/2018
1	CephalosporinaseIBA 01/2018
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2018
1	carbapenemaseIBA 01/2018
1	CarbonIBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	MaltoseIBA 01/2016
1	GlucosidasesIBA 07/2015
1	Vancomycin FDA LinkGeneric 12/2013
1	IsoenzymesIBA 10/2011
1	ProteomeIBA 04/2010
1	Metalloproteases (Metalloproteinases)IBA 04/2010
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 04/2010

Therapy/Procedure

4	Therapeutics 01/2022 - 01/2018
1	Prostatectomy (Retropubic Prostatectomy) 03/2022
1	Chemoradiotherapy 03/2019
1	Transplantation 03/2019
1	Hemofiltration 08/2018
1	Drug Therapy (Chemotherapy) 01/2018